• State of the Art Session Addresses Controversies in Antiplatelet Therapy for Patients with CAD

    Antiplatelet drugs should prevent secondary ischemic events and should be safe for long-term use – without incurring an unacceptable increase in bleeding risk. This goal remains elusive, as mortality and morbidity remain high in coronary artery disease (CAD).
    On Wednesday morning, three experts came together during a State of the Art session at the ISTH 2015 …

  • Topics on Anticoagulant-Associated Bleeding Take Center Stage

    Millions of patients take vitamin K antagonists (VKA) for the treatment and prevention of thromboembolic events, but 1-3% of patients who take them have life-threatening or fatal bleeds. Up to 2% suffer intracranial hemorrhage, which results in death in up to 79% of cases.
    “There are more than 42,000 [hospital] admissions related to serious bleeds with …

  • State of the Art: Intrinsic Coagulation Pathway May Yield Therapeutic Targets

    Major strides have been made in understanding the intrinsic coagulation pathway, producing potential new targets for therapies designed to prevent thrombus formation, according to a three-part State of the Art session held Tuesday at the ISTH 2015 Congress. Thrombi induced by medical devices are among the potential targets of effective inhibitors of the intrinsic coagulation …

  • State of the Art: Longer-acting clotting factor concentrates

    Tuesday morning’s State of the Art session on “longer-acting clotting factor concentrates” highlighted recent advances in therapeutics for hemophilia, with a focus on existing and evolving approaches to treatment. Jerry S. Powell, medical director, coagulation, for CSL Behring, discussed, among other topics,  a factor VIII (FVIII) fusion protein. Andreas Tiede of Hannover Medical School, Germany, …

  • State of the Art: Platelet Function and Dysfunction

    Three world-renowned speakers – Alan Nurden of France, Marco Cattaneo of Italy, and Barry Coller of the Unites States – came together Monday to present the state of the art regarding platelet function and dysfunction during a session named for 1981 ISTH Congress President  J. Fraser Mustard, who was a pioneer in the area of …

  • State-of-the Art review papers and abstracts available on USB sticks

    This year, for the first time, the International Society on Thrombosis and Haemostasis (ISTH) and the Journal of Thrombosis and Haemostasis (JTH) have elected to provide State-of-the-Art review papers on USB sticks, available at the ISTH booth (#1036). ISTH regular members and JTH subscribers will receive a print version in the mail following the ISTH …